A seizure is a transient occurrence of signs and/or symptoms resulting from abnormal excessive or synchronous neuronal activity in the brain.
Epilepsy is considered to be present when 2 or more unprovoked seizures occur in a time frame of longer than 24 hr
An epileptic encephalopathy is an epileptic syndrome in which there is a severe EEG abnormality resulting in cognitive and other impairments.
incidence of neonatal seizure is 1.8–3.5 % of live births in the United States,
Two types
- Focal ( previously known as partial): initial activation limited to one part of brain. Simple focal are without altered conciousness while complex seizure are with altered conciousness such type also k/a focal dyscognitive disorder
- Generalised: both sides of cerebral hemisphere are involved.
- 30% of chiildren who have a febrile seizure can develop epilepsy
- Febrile seizure: gneralised , fever of 38 deg, no post ictal activity, duration less than 15 min.
- Seizure can arise from brainstem or hemisphere, seizure from one region are less likely to spread to other due to physiological demyelination seen in infants.
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